By George Morstyn (auth.), Graham Molineux, MaryAnn Foote, Tara Arvedson (eds.)
Granulocyte colony-stimulating issue (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow. improvement of recombinant human G-CSF has had a profound impression at the remedy of many ailments, together with serious persistent neutropenia and melanoma, and has enabled peripheral stem mobile transplantation to supplant bone marrow transplantation within the autologous environment.
This Milestones in Drug Therapy quantity describes the adventure of the final twenty years of remedy with recombinant human G-CSF, together with the fundamental technological know-how, using recombinant human G-CSF in either the oncology and nononcology settings, and the security and economics of its use. a few of the authors have been the unique investigators of recombinant human G-CSF and different authors are key researchers who supply their outlook for the subsequent twenty years to be used of and examine with recombinant human G-CSF.
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