Download E-books Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models PDF

By Joel S. Owen, Jill Fiedler-Kelly

This booklet offers a common, hands-on advent to the Nonlinear combined results Modeling (NONMEM) method, the main strong software for pharmacokinetic / pharmacodynamic analysis.
• Introduces considered necessary history to utilizing Nonlinear combined results Modeling (NONMEM), overlaying facts specifications, version construction and overview, and qc aspects
• Provides examples of nonlinear modeling thoughts and estimation fundamentals with dialogue on  the version construction strategy and purposes of empirical Bayesian estimates within the drug improvement environment
• Includes exact chapters on info set constitution, constructing regulate streams for modeling and simulation, version functions, interpretation of NONMEM output and effects, and caliber control
• Has datasets, programming code, and perform workouts with ideas, on hand on a supplementary web site

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