By Golan Yona
Introduction to Computational Proteomics introduces the sector of computational biology via a concentrated process that tackles different steps and difficulties concerned with protein research, class, and meta-organization. The booklet starts off with the research of person entities and works its means throughout the research of extra complicated entities, from protein households to interactions, mobile pathways, and gene networks.
The first a part of the ebook provides equipment for determining the development blocks of the protein area, resembling motifs and domain names. It additionally describes algorithms for assessing similarity among proteins in keeping with series and constitution research in addition to mathematical types, reminiscent of hidden Markov versions and aid vector machines, which are used to symbolize protein households and classify new cases.
The moment half covers tools that examine larger order constitution within the protein house throughout the program of unsupervised studying algorithms, equivalent to clustering and embedding. The e-book additionally explores the wider context of proteins. It discusses tools for studying gene expression facts, predicting protein-protein interactions, elucidating mobile pathways, and reconstructing gene networks.
This publication offers a coherent and thorough advent to proteome research. It bargains rigorous, formal descriptions, in addition to distinct algorithmic ideas and types. every one bankruptcy contains challenge units from classes taught by means of the writer at Cornell college and the Technion. software program downloads, facts units, and different fabric can be found at biozon.org
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