By Hsiu-Chiung Yang, Wu-Kuang Yeh, J. R. McCarthy
Sets the level for advances in drug discovery utilizing the newest enzyme technology
Reviewing new and rising functions of enzyme expertise in drug discovery, this ebook highlights probably the most promising parts of pharmaceutical and biotechnology learn. It covers enzyme assay know-how, usage of enzymology for prodrug layout, and the applying of enzymes as healing brokers. specialist reports spotlight how our most modern knowing of enzymology is used to enhance new useful functions in drug discovery and design.
Filled with case reports, Enzyme applied sciences: Pluripotent avid gamers in researching healing Agents allows readers to raised comprehend the varied services of enzymes and grasp particular functions in drug discovery learn. as well as small molecule drug discovery, the booklet explores new advancements in enzymes as healing brokers for genetic disorders.
- Section A, Enzymes – crucial Workhorses in Pharmaceutical examine, deals help in selecting the right enzyme pursuits for drug discovery, designing enzyme inhibitors for healing brokers, and comparing selective enzyme inhibitors.
- Section B, Enzymes – integral instruments for making improvements to Druggability, units forth the rules along real-world examples of exploiting particular homes of enzymes to layout profitable prodrugs.
- Section C, Enzymes – robust guns for Correcting Nature's blunders, offers new insights on making use of enzymes as healing brokers or diagnostic instruments to regard genetic disorders.
Chapters are contributed through best specialists from all over the world. Their contributions are in line with a radical assessment of the present literature in addition to their very own research.
Reviewing our most up-to-date realizing of the character of enzymes and their function in drug discovery, this ebook is usually recommended for researchers in prescribed drugs and biotechnology in addition to for researchers in enzymology, biochemistry, molecular biology, and medicinal chemistry.
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